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As for side effects, some patients experience bloating, fullness, constipation, and nausea as side effects with either of these products
Some business losses include the pause of patient enrollment in a Phase III tolebrutinib trial by the FDA due to some potential side effects from the treatment, as well as the cessation of the global clinical development program of amcenestrant for breast cancer in August 2022
Some observational data suggest possible benefit, but randomized trials have not confirmed a direct protective effect
Debatable Pro / Con: increased arrousal, more actively sexually active
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