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doi: 10.1684/mrh.2020.0465 124 JacksonC

Four-Octyl Itaconate Protects Chondrocytes against H(2)O(2)-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating Nrf2 Signaling

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Its metabolic functions include: Enhanced immune function Elimination of toxins Elimination of carcinogens Antioxidant cell protection Protections against ionizing radiation DNA synthesis and repair Protein synthesis Prostaglandin synthesis Amino acid transport Enzyme activation and regulation These functions can be summarized into three general categories: 1