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This study investigated the effect of combined treatment with the FGF21 analog zalfermin and the glucagon-like peptide-1 receptor agonist semaglutide on body weight and plasma and liver biochemistry and histology in a mouse model of MASH

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Saylor Key Takeaways Semaglutide generated the broadest menstrual adverse event signal profile in a FAERS analysis of reproductive-aged patients, including heavy bleeding, menstrual clots, and anovulatory cycles

Ongoing clinical research continues to study how these pathways interact to produce meaningful outcomes for patients