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USA 110 , 90669071 (2013)
How to Switch from Semaglutide to Tirzepatide Stepwise Dose Adjustment When switching from semaglutide to tirzepatide, it is best to stop semaglutide and initiate tirzepatide at a low dose, typically 2.5 mg weekly, regardless of the semaglutide dose
The current analysis showed consistent reductions with semaglutide in the risk of MACE versus placebo across baseline eGFR and UACR subgroups, which is in line with a meta-analysis that evaluated CVOTs showing that GLP-1RAs reduced the risk of MACE versus placebo, regardless of baseline eGFR [7]
In most cases, GLP-1 medications are used to treat obesity and diabetes both of which are managed in primary care
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