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The Gut-Brain Axis and Emotional Eating GLP-1 impacts the gut-brain axis an intricate communication system between the gut microbiota and brain via neural, immune and hormonal signalling (Singh et al, 2024)

Food stays in the stomach longer, which contributes to feelings of fullness and reduced caloric intake

Diabetes (2014) 63(2):47182.10.2337/db13-0903 35 WichmannAAllahyarAGreinerTUPlovierHLundnGLarssonTet alMicrobial modulation of energy availability in the colon regulates intestinal transit

The 8 to 12 week window often marks a shift into more consistent weekly weight loss, with patients averaging 1 to 2 pounds per week as appetite suppression deepens and behavioral changes solidify