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Phase 1 hydroxylation via CYP1A1 and CYP1B1

Notably, myo-inositol is a key molecule in FSH signaling and oocyte maturation, and its supplementation has been shown to improve the metaphase II (MII) oocyte rate and fertilization rate, particularly in women with PCOS and non-obese PCOS (Zhang et al., 2025)

Its used on demand rather than daily, so cumulative exposure is limited compared with maintenance medications