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Although the optimal dose of LC supplementation for myocardial infarction is 3 g/day in terms of all-cause mortality [90], even lower LC intake elevates fasting plasma TMAO [16,17,18, 58, 59], which is ten-fold higher than control after 3 months of supplementation [16, 17]

This high-potency dose supports cellular defence against oxidative stress, promotes healthy liver detox pathways, and helps maintain respiratory and immune function.*

Behav Brain Res 458:114728

How much of an oral dose reaches circulation varies between individuals, and IV delivery can produce higher circulating levels than an equivalent oral dose