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Notably, GLP-1RA liraglutide has been proven to repair lysosomal function and boost lysosomal biogenesis in HFD mice and hepatocytes by activating the transcription factor EB (TFEB), which is a vital regulator of lysosomal function [282]
McGarry A, Rosanbalm S, Leinonen M, Olanow CW, To D, Bell A, et al
This mechanism helps with weight loss but can also trigger nausea, constipation, or diarrhea in otherwise healthy people
In particular, Frssing et al
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