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In the UK, hydroxocobalamin is the standard form used for intramuscular injections, and routine monitoring of serum B12 levels during replacement therapy is generally not required once treatment is established

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Even though cobalt is a major component of an essential vitamin, about 2% of the general population is allergic to it, according to DermNetNZ

Copper ions delivered by GHK-Cu also demonstrate up to 90% inhibition of type 1 5-alpha reductase at specific concentrations