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They are biologically plausible, but they do not amount to a large, independently replicated clinical evidence base
The ORF9b could further manipulate host mitochondria by releasing mitochondrial DNA (mt-DNA) into the cytoplasm to activate mt-DNA-induced inflammasome and suppress innate as well as adaptive immunity 162
Addressing these issues, natural compounds and antioxidants have shown promise in mitigating oxidative damage
Intracellular S-palmitoylation is catalyzed by a zinc-finger Asp-His-His-Cys domain-containing (zDHHC) family of palmitoyl acyltransferases (PATs) 10
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