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57,59 Exenatide, a synthetic peptide with 50% sequence homology to GLP-1, is resistant to dipeptidyl peptidase-4-mediated degradation 54 and was the first GLP-1RAs approved by the US Food and Drug Administration (FDA) for T2DM treatment in 2005
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No research demonstrates that GLP-1 medications reduce thyroid antibody levels, slow autoimmune thyroid destruction, or improve thyroid function in patients with Hashimoto's disease
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