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Management options may include dose adjustment, additional support for managing gastrointestinal side effects, referral to diabetes psychology services, or consideration of alternative diabetes medications if symptoms are genuinely medication-related and problematic

Some patients experience metabolic adjustment during the fadeout phase, including a temporary increase in food intake or weight gain of 13 pounds

Lowered blood pressure (slightly) Research found that berberine consistently lowered the top blood pressure number (systolic pressure) in most people studied but generally didn't affect the bottom number (diastolic pressure)except when higher doses were used

Patients with Type 2 Diabetes Retatrutide is under investigation for type 2 diabetes management