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However, the extract produced a significant 15% reduction in TMAO response in female participants of premenopausal age and male participants ( n = 13), indicating potential sex-dependent cardiovascular benefits from polyphenol interventions targeting the gut microbiome-TMAO pathway
All above is consistent with anti-inflammatory effect of GIPR/GLP1R agonism, which plays a role in improving atherosclerosis lesion severity
and T.Y
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