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Published 2025 Feb 5

This protective mechanism, while crucial for brain health, presents a significant challenge for drug delivery, hindering the development of therapies that target central GLP-1 pathways

Strategies for older women: Work with your fertility specialist to explore options like shorter optimization periods of 3-4 months on GLP-1s rather than 6 months, or potentially using a shorter washout if appropriate for your situation2 months instead of 3 (this decision should be made with your doctors guidance)