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It is important to contextualise these results carefully: Phase 2 trials involve relatively small, controlled populations and are not sufficient on their own to establish a medicine's full safety profile or its suitability for broad clinical use
Most importantly, communicate with your prescribing clinician about any symptoms
Hers doesnt have the same kind of high-profile testimonials
For example, estrogen signaling has been shown to enhance the anorexigenic effects of GLP-1 RAs by modulating central pathways involved in food reward, which could account for the more pronounced weight loss observed in premenopausal women [49, 50]
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