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A person with a BMI of 28 and a history of gestational diabetes may benefit from one of these medications to lose weight while concomitantly mastering lifestyle behaviors, and then transition off the weight management medications to lifestyle alone, says Linda Gigliotti, MS, RDN, CDCES, CSOWM, an obesity and weight management specialist based in Irvine, California
Autophagy, on the other hand, involves the degradation of damaged organelles or proteins through autophagosomes, and while it can be protective under stress conditions, excessive autophagy can also lead to cell death
Read more about why weight regain happens after stopping GLP-1 and how to avoid it
However, recent drug discoveries and targeted therapies indicate evidence for durable remissions but no guaranty can be given yet on drug resistance 2
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