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GLP-1 receptor agonists in mood disorders: a psychiatric perspective

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The release of GLP-1 follows a biphasic pathway: an initial peak mediated by neural signalling, followed by a second phase which is triggered by direct mechanical stimulation of L-cells, as nutrients pass through the gut (18)

On February 6, FDA announced its intention to take decisive enforcement action against non-FDA-approved compounded GLP-1 drugs, specifically identifying restrictions on GLP-1 active pharmaceutical ingredients (APIs) used in mass-marketed compounded products