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Evidence suggests it may promote neuroprotection, regulate inflammation, and influence mood and cognition, with potential clinical relevance for neurodegenerative and psychiatric disorders
However, while central pharmacodynamics is an important factor influencing drug intake, peripheral pharmacokinetics can also have a profound effect on intake and even neural response to the same drug 56,57
This has resulted in the prevalence of studies with correlation, but causation is still uncertain
By weeks 48 at a stable dose, the majority of users adapt and symptoms either disappear or become consistently mild
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