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The authors administered oral Dihexa to APP/PS1 transgenic mice (a standard amyloidopathy model of Alzheimers disease) and showed that brain AngIV levels were elevated relative to wild-type after Dihexa administration, that spatial learning and memory were restored on Morris water maze testing, that hippocampal neuronal density and synaptophysin protein expression were preserved, that astrocyte and microglial activation were reduced, and that pro-inflammatory cytokines (IL-1, TNF-) decreased while anti-inflammatory IL-10 increased
Such distinction from other diluents is explained in guides comparing bacteriostatic water vs reconstitution solution
It is derived from a partial sequence of the body protection compound and is beneficial for repairing tendons, ligaments, the digestive tract, and even the central nervous system
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