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Patients on tirzepatide were twice as likely to lose at least 25% of their body weight, and nearly one in five (19.7%) lost 30% or more, compared to fewer than one in fourteen (6.9%) on semaglutide.[1] Both medications also improved blood pressure, blood sugar, and cholesterol levels, with greater improvements seen in the tirzepatide group, which tracked with the larger weight reduction.[1] The safety profiles were similar
Access to these treatment in 2025 is expanding through telehealth programs like MEDVi
NICE guidance does not reference berberine in any clinical pathway for diabetes (NG28), cardiovascular disease (NG238), obesity, or metabolic syndrome
Parker, founder of Forge Fitness & Nutrition Coaching, with more than 25 years of experience in exercise science, nutrition, habits, and GLP-1 fitness programming
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