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Plant J 35:2732 Wachter A, Wolf S, Steininger H, Bogs J, Rausch T (2005) Differential targeting of GSH1 and GSH2 is achieved by multiple transcription initiation: implications for the compartmentation of glutathione biosynthesis in the Brassicaceae

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When healthy cells generate energy (adenosine triphosphate, or ATP) through the mitochondrial electron transport chain, they naturally produce highly reactive oxygen species (ROS) as a metabolic byproduct