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Activation of the Nrf2/FPN pathway could block ferroptosis and thus reduce myocardial ischemia-reperfusion injury (IRI) in diabetic rats[132]
Wu et al., 2019), suggesting a feedback relationship in which transcription promotes eccDNA formation, and gene amplification, which in turn can further elevate transcription
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When patients express interest in combining these substances, clinicians should conduct a thorough assessment including medical history, current medications, baseline kidney function, and treatment goals
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