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The boost in insulin helps lower glucose levels, which helps control type 2 diabetes

Melanocortin agonism stimulates melanocytes, and a related report describes eruptive nevi a sudden crop of new moles associated with an -MSH analog, exactly the kind of pigment-cell proliferation one would predict from over-stimulating this pathway

This is clinically significant because metabolic dysfunction-associated steatotic liver disease (MASLD) previously known as non-alcoholic fatty liver disease (NAFLD) is estimated to affect approximately 2530% of adults in the UK (British Liver Trust), and can progress to cirrhosis and liver failure if untreated

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