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Injections skip that system and deliver most of the dose
The documented label and trial protocol does not use a single fixed dose
The clinical data on how common this is From the published SURPASS and SURMOUNT trials: Mounjaro has a slightly higher injection site reaction rate than other GLP-1 medications, likely because of the dual agonist mechanism (more immune recognition events) and the larger injection volume (0.5 mL vs 0.25 to 0.375 mL for semaglutide)
Managing chronic conditions like diabetes and obesity continues to evolve as new treatments emerge
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