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The Charmm36 force field was utilized to generate the topology for the protein [33], while the ligand topology parameters were generated using the CHARMM General Force Field (CGenFF) program [34]
While several risk factors including BMI and immune cells may be biologically related to insomnia and cognitive functionality, they were not identified as significant mediators in the present study based on the available data
In the earlier stages, surgical removal is often the only treatment thats necessary
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