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Children with certain GSTM1-null genotypes may be less able to handle oxidative stress and more vulnerable to prenatal exposures like medications
In this regard, it has been shown that tamoxifen, a type of selective estrogen receptor modulator (SERM) that acts as a competitive antagonist or as a partial agonist depending on the cell type, favors the repair of demyelinated lesions in the CNS by increasing the mRNA levels of myelin basic protein (MBP) and 2, 3-Cyclic nucleotide 3-phosphodiesterase (CNP), two genes highly expressed during oligodendroglial differentiation (Gonzalez et al., 2016)
Yes, the levels of glutathione in the body can be increased through a diet rich in sulfur-containing foods, such as garlic, onions, broccoli, and cabbage
Chauhan et al., 2012
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