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Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53

This study suggests that apigenin has a pleiotropic effect, leading to the activation of pro-proliferative and pro-neurogenic factors including Mki67, nestin, Sox2, and Pax6

Its theoretical mechanisms and observed effects in animal studies have led to interest in applications for companion animals, though veterinary use remains investigational