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Luger et al
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10 Conclusion and future perspectives The immunometabolic crosstalk between tumor-associated macrophages (TAMs) and ferroptotic cancer cells has emerged as a defining regulator of tumor fate, influencing progression, metastasis, immune evasion, and therapeutic response
These cells significantly influence immune suppression in cancer, contributing to tumor vascular development, therapy resistance, and increased metastasis, all of which are well supported by existing evidences
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