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Metabolic remodeling Cardiac metabolic remodeling, characterized by metabolic inflexibility, lipotoxicity, glucotoxicity, impaired mitochondrial respiration, and insulin resistance, plays a crucial role in the development of obesity- and diabetes-related cardiac dysfunction
Example 13 removal of Lys side chain protecting groups The fully protected peptide resin obtained in example 9 was subjected to the same procedure as in example 11 to thereby complete the removal of the Lys side chain Alloc protecting group
l-valine could therefore potentially have entered GLUTag cells by mechanisms normally associated with basolateral uptake, which may affect the stimulatory pathway
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