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No evidence exists for probiotics replacing semaglutide, for specific CFU counts being necessary for semaglutide users (as opposed to general probiotic dosing), or for probiotics eliminating all GI side effects
India typically reviews a drug after it has US or European approval and full trial data available
gentle swirling is sufficient if mixing is required Minimise the number of times the vial is accessed, as repeated needle punctures increase contamination risk Label the vial clearly with the date and time of reconstitution, and with the sponsor-validated beyond-use date Follow all additional handling instructions specified in the IMP label or protocol These measures help to slow the degradation processes described above
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