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(6) Hu R, Wang Z, Peng Q, Zou H, Wang H, Yu X, Jing X, Wang Y, Cao B, Bao S, Zhang W, Zhao S, Ji H, Kong X, Niu Q

Experimental evidence from knockout models suggests that reduced NNMT activity is associated with resistance to tumor formation, leading to speculation about a possible role for this enzyme in cancer biology

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This inter-individual metabolic heterogeneity is further finely regulated by multiple factors, including host genetic polymorphisms, dietary habits, immune status, and disease stage