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Karsdal MA, Byrjalsen I, Azria M, et al

Oxid Med Cell Longev 2018:7924021

doi: 10.1136/bmj.c869 Summary Keywords obesity, GLP-1, GLP-1 receptor analog, exenatide, pediatrics, glycemic control, GLP-1 receptor agonist, treatment Citation Stenlid R, Cerenius SY, Wen Q, Aydin BK, Manell H, Chowdhury A, Kristinsson H, Ciba I, Gjessing ES, Mrwald K, Gomahr J, Heu V, Weghuber D, Forslund A and Bergsten P (2023) Adolescents with obesity treated with exenatide maintain endogenous GLP-1, reduce DPP-4, and improve glycemic control

Important questions remain unanswered, including optimal dosing regimens, which patient populations might benefit most, long-term efficacy, and whether effects persist after medication discontinuation