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Although the enrichment of L-cells by pharmacological agents can be a novel approach for improving insulin secretion, glucose tolerance and the treatment of T2DM, more research for the specific differentiation of L-cells and the translation of in vitro and animal data to humans, are needed for the success of this approach

Epiploic appendagitis most commonly affects appendages along the descending colon (24.5%), sigmoid (22.6%), cecum (14.5%), or the ascending colon (14.5%) [4]