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Twice daily exenatide treatment combined with metformin maintained glycemic control for longer periods and in a higher proportion of treated patients than glimepiride in an open-label, randomized controlled study in patients with inadequately controlled type 2 diabetes with up to 4.5 years of follow-up [47]
Randomized controlled trials are the next step
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The food intake of our GDF8/ActA control group was unchanged from the vehicle in our NHP study (Fig
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