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Muscle loss and bone weakening Numerous studies have documented that rapid weight loss from Ozempic and other medications can cause significant muscle loss, especially in people who dont increase their protein intake

Thus, several studies have demonstrated the presence of prohormone convertase 1/3 [PC1/3, the processing enzyme that cleaves proglucagon to generate GLP-1 (105)] and fully processed GLP-1 in rodent and human -cells and islets in culture (106110), and GLP-1 can be detected in the media, suggesting that it is secreted from the -cells

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