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Even though animal models show benefits from melatonin supplementation on depressive-like behavior, clinical evidence is inconsistent vis--vis prophylactic or therapeutic benefits of melatonin or melatonin agonists in depression

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Endotheliopathies and significant clotting pathologies are important clinical features of acute COVID-19 [338,339,340]

1 Introduction With an aging global population, it is estimated that 2.2 billion people worldwide are suffering from visual dysfunction, which severely impedes the individuals quality of life and poses threats to public health (1)