You must use a backup (non-oral) method for 4 weeks after starting and 4 weeks after each dose increase
Can I skip the titration and start at a higher dose
FP reports the receipt of grants/research support from AstraZeneca, Eisai, and Roche, and receipts of honoraria or consultation fees from Amgen, AstraZeneca, Daichii Sankyo, Celgene, Eisai, Eli Lilly, Exact Sciences, Gilead, Ipsen, Italfarmaco, Menarini, MSD, Novartis, Pierre Fabre, Pfizer, Roche, Seagen, Takeda, and Viatris, all outside the submitted work
In 1972 Habener became an investigator at the same hospital and Harvard Medical School