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It ensures no structural degradations or heavy impurities remain in the vial
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These can include changes to the nervous system and feedback mechanisms involved in appetite signaling, which could reduce caloric intake and result in fatigue
The following groups have typically been excluded from clinical trials or would require careful specialist assessment, reflecting cautions seen across related approved medicines: A personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2): This is a theoretical concern that has led to exclusion from trials of GLP-1 receptor agonist therapies, based on animal data
