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A 7-fold increase in bioavailability means that a 500 mcg oral dose of the arginate form could deliver the equivalent systemic exposure of approximately 3,500 mcg of the acetate form taken orally

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Preclinical studies reveal that CBDA exhibits distinct biological activity that is not fully replicated by CBD: Serotonin receptor modulation (5-HT1A agonism): CBDA demonstrates potent activity at 5-HT1A receptors, which may underlie its anti-nausea and anti-emetic effects observed in animal models

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