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The risk-benefit balance may be less favourable for people near a normal BMI than for those who are clearly obese

It is worth noting that some of the patients with low dosages discontinued the treatment early (when the medication dosage is supposed to be titrated up), so they would not have had the chance to reach the recommended maintenance dosage because of treatment discontinuation, he said

Visceral and total reduction in fat mass was also significantly higher in the GLP-1 agonist treated patients

Currently, the FDA has approved three different GLP-1s for the long-term treatment of obesity: Liraglutide (Saxenda), Semaglutide (Wegovy), and Tirzepatide (Zepbound)