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What raises concerns are some of the recent reports of serious ADRs associated with GLP-1RAs: (i) Pfizers disclosure of elevated aminotransferases in users of lotiglipron (a novel oral GLP-1RA) is indicative of hepatocellular injury [11]
What the research shows: In the landmark STEP clinical trials, patients taking semaglutide lost an average of 15% of their body weight over 68 weeks
Tirzepatide (Mounjaro, Zepbound) is a fully synthetic peptide medication approved by the FDA for type 2 diabetes and chronic weight management
Mounjaro is contraindicated in people with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
US$ 27.80
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US$ 26.10
US$ 25.00
