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In the present study using obese mice fed HFD for 5 weeks or longer, food intake in LP (7:3019:30) was approximately doubled, whereas that in dark period (DP, 19:307:30) unaltered, exhibiting LP-specific hyperphagia accompanied by daily hyperphagia (Figs
However, these agents increase risk of intra-operative pulmonary aspiration according to a case report secondary to delayed emptying and presence of gastric residues despite fasting (108, 108) To prevent these events, the recent recommendations from the American Society of Anesthesiology guidelines suggest discontinuing GLP-1 receptor agonists 1 day prior in patients on daily dosing and 1 week prior in patients on weekly injection dosing (108)
