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Bai XJ, Hao JT, Zheng RH, et al
Patients with these mutations may benefit from more personalized treatment strategies and close clinical monitoring to ensure optimal thyroid hormone replacement
Key advancements in peptide technology for triple receptor agonism: Application of computational modeling to peptide-receptor binding Fatty acid substitution for extended stability and duration -helical design for superior receptor fit Structure-based design to hone drug action and safety Engineering peptides that simultaneously bind and stimulate multiple receptors Clinical Implications With retatrutide, a triple receptor agonist that has been studied in clinical trials for obesity and metabolic diseases, including type 2 diabetes and MASLD
