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Oral and sublingual formulations are promising but are still establishing their efficacy profiles through ongoing research

Second, and this surprises most people, the discontinuation rate due to gastrointestinal side effects was actually lower with tirzepatide than with semaglutide

Reasons for using compounded drugs include: When someone has an allergy to an ingredient in a commercial drug A person needs a medication with a different formulation (like a pill version of an injection, due to medical reasons) Theres a shortage of FDA-approved medications While compounded drugs are typically less expensive than branded versions, they do not undergo the same rigorous FDA approval process as commercial drugs

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