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1E, F), making it difficult to extricate the other phenotypes potentially caused by the loss of GSH

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Specifically, reduced expression and phosphorylation of ERK1/2, JNK1, and P38 MAPK were observed, along with decreased expression of pro-angiogenic factors (VEGF), fibroblast growth factor receptors (FGFR-1), transforming growth factor 1 (TGF-1), Snail, and hypoxia-inducible factor 1 (HIF-1)

Preventative strategies involve eating smaller frequent meals, avoiding carbonated beverages and high-fat foods, remaining upright after eating, and following the prescribed dose escalation schedule