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Therapeutic targeting of hepatic ACSL4 ameliorates NASH in mice
PT-141 was originally discovered as a side effect during research on melanotan II, a synthetic tanning peptide
GLP-1 Timeline: From Diabetes to Pediatric Weight Management 2005: First GLP-1 medications approved for Type 2 diabetes in adults 2014: FDA approves Saxenda (liraglutide) as the first GLP-1 for weight loss 2022: Wegovy approved for adolescents 12 and older 2023: American Academy of Pediatrics endorses GLP-1s for pediatric obesity 2025: FDA considering approval for children as young as 6 years old Though the FDA approved Saxenda as the first GLP-1 for weight loss back in 2014, it wasnt until the last few years that the popularity and availability of these medications for obesity have skyrocketed
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