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(PubMed) Franke B, Vermeulen SH, Steegers-Theunissen RP, et al
doi:10.1038/21224 61
(10 g or 10 ng/kg/day), topical (1.0 g in cream), or per-oral (0.16 g/mL in drinking water) over 90 days and described directional improvements across biomechanical, functional, macroscopic, and histological endpoints, though specific effect sizes and p-values are not reported in the abstract
Cagrilintide One phase 2 trial demonstrated that weekly injections of cagrilintide induced 10.8% weight loss over 26 weeks, compared to 9% with liraglutide, and 3% with placebo (mean age 52.3 years, with no upper age limit)
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