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If you just administer at night the body increases melanin production in areas with greater natural melanocyte activity, genitals, freckles, moles, etc leading to many of the sides reported with MT, but if used in conjunction with UV, the body has mechanisms to increase melanin production and melanocyte activity in areas that need the production to protect from UV photodamage, such as the skin

The optimal dose is the lowest dose that produces the desired clinical effect with acceptable tolerability

HERE'S HOW: Insulin Release: The medications stimulate the release of insulin from the pancreas in a glucose-dependent manner

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