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In vivo, SLU-PP-332 increases oxidative fiber markers (for example, type IIa), cytochrome-c content, mitochondrial DNA abundance, and expression of OXPHOS genes

10.1111/j.1528-1157.1994.tb02546.x

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In this context, also polymeric NPs have been employed to efficiently deliver plant-based therapeutics to the brain by crossing the BBB with some promising results, as exhaustively reviewed by Ovais et al