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The data supporting ursodiol is strong
Regulatory frameworksFDA approval pathways, DEA scheduling considerations, and pharmacist oversightexist to ensure medications are prescribed by licensed providers who can assess individual risk factors, perform baseline labs, and titrate dosing safely over months
Many people like this method because it is direct and gets absorbed well
Serious risks include systemic infections in immunocompromised patients, and the FDA advises against use in critically ill patients and preterm infants due to potential harm
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